OJPHI: Vol. 5
Journal Information
Journal ID (publisher-id): OJPHI
ISSN: 1947-2579
Publisher: University of Illinois at Chicago Library
Article Information
©2013 the author(s)
open-access: This is an Open Access article. Authors own copyright of their articles appearing in the Online Journal of Public Health Informatics. Readers may copy articles without permission of the copyright owner(s), as long as the author and OJPHI are acknowledged in the copy and the copy is used for educational, not-for-profit purposes.
Electronic publication date: Day: 4 Month: 4 Year: 2013
collection publication date: Year: 2013
Volume: 5E-location ID: e15
Publisher Id: ojphi-05-15

Tracking Dynamic Water-borne Outbreaks with Temporal Consistency Constraints
Skyler Speakman*
Yating Zhang
Daniel B. Neill
Carnegie Mellon University, Pittsburgh, PA, USA
*Skyler Speakman, E-mail: skylerspeakman@gmail.com


We describe a novel graph-based event detection approach which can accurately identify and track dynamic outbreaks (where the affected region changes over time). Our approach enforces soft constraints on temporal consistency, allowing detected regions to grow, shrink, or move while penalizing implausible region dynamics. Using simulated contaminant plumes diffusing through a water distribution system, we demonstrate that our method improves both detection time and spatial-temporal accuracy when tracking dynamic water-borne outbreaks.


Space-time scan statistics are often used to identify emerging spatial clusters of disease cases [1,2]. They operate by maximizing a score function (likelihood ratio statistic) over multiple spatio-temporal regions. The temporal component is typically incorporated by aggregating counts across a given time window, thus assuming that the affected region does not change over time. To relax this hard constraint on spatial-temporal “shape” and increase detection power and accuracy when tracking spreading outbreaks, we implement a new graph-based event detection approach which enables identification of dynamic clusters while enforcing temporal consistency constraints between temporally-adjacent spatial regions.


In the subset scanning framework, temporal consistency constraints may be interpreted as influencing the prior probability pit of location i being included in the optimal spatial subset at time t. We model this prior probability for each location as log(pit/(1−pit))=B0+B1Xit−1 where Xit−1 is 1 if location i was included in the previous time step and 0 otherwise, and maximize the penalized log-likelihood ratio over dynamic spatio-temporal regions. Our efficient algorithm incorporates these constraints into the Graph-Scan method [3] by iteratively optimizing the spatial subset for each time slice conditioned on the previous and next slices. Each individual optimization step is made possible by expressing the score function as an additive function (conditioned on the relative risk), which enables the priors to be included while maintaining computational efficiency.


Outbreak plumes were simulated in a water distribution system for 12 one-hour periods. We assumed noisy binary sensors (with 10% false positive and 90% true positive rates) observed hourly at each pipe junction. Our method (“Dynamic”) was compared to the “Static” method, which aggregates counts across time for each spatial region and is therefore constrained to only return temporal cylinders, and the “Independent” method, which separately optimizes the spatial subset for each time slice without taking temporal consistency into account. The methods were evaluated on spatial-temporal overlap (Figure 1), defined as the number of sensors contained in both the detected and affected space-time regions divided by the number of sensors in either the detected or affected space-time regions. A measure of 1 is a perfect match of spatial subsets across each time window and 0 would reflect disjoint space-time regions. Additionally, average time to detect an outbreak (at a fixed false positive rate of 1/month) was 4.24, 4.56, and 6.65 hours for the dynamic, static, and independent methods respectively.


Relaxing constraints on spatial-temporal region shape must be done carefully. Allowing independent selection of spatial regions loses important temporal information while hard constraints on the spatial-temporal region will fail to capture the dynamics of the outbreak. Our approach for detecting dynamic space-time clusters, while incorporating temporal consistency constraints, addresses these issues and results in higher spatial-temporal accuracy and detection power.


This work was partially supported by NSF grants IIS-0916345, IIS-0911032, and IIS-0953330.

1.. Kulldorff M. A spatial scan statisticCommunications in Statistics: Theory and Methods 1997;26(6):1481–1496.
2.. Neill DB. Fast subset scan for spatial pattern detectionJournal of the Royal Statistical Society (Series B) 2012;74(2):337–360.
3.. Speakman S, Neill DB. Fast graph scan for scalable detection of arbitrary connected clustersAdvances in Disease Surveillance. 2010

[Figure ID: f1-ojphi-05-15]

Spatial-temporal overlap for three competing detection methods

Article Categories:
  • ISDS 2012 Conference Abstracts

Keywords: outbreak detection, space-time scan statistics, dynamic event tracking, penalized likelihood ratio.

Online Journal of Public Health Informatics * ISSN 1947-2579 * http://ojphi.org